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CBP20 Rabbit pAb说明书

发表时间:2023-12-26

CBP20 Rabbit pAb

Application: WB,ICC/IF

Alternative NamesSTAT1; Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3

components p91/p84

Gene Name    

NCBP2

Alternative

Names

Nuclear cap-binding protein subunit 2; 20 kDa nuclear cap-binding protein; Cell proliferation-inducing gene 55 protein; NCBP 20 kDa subunit; CBP20; NCBP-interacting protein 1; NIP1; NCBP2; CBP20; ORF   Names: PIG55

SwissProt ID

P52298

Gene ID

22916

 

 

 

Background

In eukaryotes, the majority of mRNAs have an m(7)G cap, which is added cotranscriptionally and plays a critical role in many aspects of mRNA metabolism. The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex (CBC). CBC consists of two cap binding proteins, CBP20 and CBP80, which mediate the stimulatory functions of the cap in pre-mRNA splicing, 3' end formation and U snRNA export. The genes CBC1 and CBC2 encode CBP80 and CBP20, respectively. CBP80 comprises three domains, each containing a MIF4G domain. CBP20 has an RNAP fold and associates with the second and third domains of CBP80.

Product

Categories

Primary antibody

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB, IHC-P, ICC/IF,IP

Dilution

Ratio

WB: 1/500-1/1000  IHC: 1/50-1/200  IF: 1/50-1/200  IP: 1/50-1/100

Clonality

Polyclonal Antibody

Isotype

IgG

Immunogen

Synthetic peptide corresponding to amino acids N-terminus of Human CBP20.

Purification

Affinity Purified

Conjugation

Unconjugated

Modification

Unmodified

Form

Liquid

 PROPERTIES

NOTE:The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.